CAS No.: 3895-92-9
盐酸白屈菜红碱 Catalog No. CSN10607
Synonyms: 盐酸白屈菜红碱
Chelerythrine Chloride is a potent, cell-permeable inhibitor of protein kinase C (IC50 = 660 nM) and competitive with respect to the phosphate acceptor and non-competitive with respect to ATP.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
靶点 PKC
IC50:660nM- 描述
动物研究 毒性数据 (半致死量) LD50: 18.5mg/kg (mouse)
- 参考文献
- [1] Li W, Fan T, et al. Effect of chelerythrine against endotoxic shock in mice and its modulation of inflammatory mediators in peritoneal macrophages through the modulation of mitogen-activated protein kinase (MAPK) pathway. Inflammation. 2012 Dec;35(6)
- [2] Pěncikova K, Kollar P, et al. inflammatory gene expression in THP-1 cell line. Phytomedicine. 2012 Jul 15;19(10):890-5.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 3895-92-9 | 储存条件 |
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| 分子式 | C21H18ClNO4 | 运输 | 蓝冰 | |||||
| 分子量 | 383.82 | 别名 | 盐酸白屈菜红碱 | |||||
| 溶解度 |
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动物实验配方 |
